As a result of this hormone imbalance, affected males have incompletely developed secondary male sex characteristics. As they grow older, they tend to become taller than average. Looking Ahead Because boys with Klinefelter syndrome can have problems with schoolwork and sports, they may feel like they don't fit in with other kids their age. Physical and occupational therapy may be helpful in affected boys with coordination and muscle problems. Commercial testosterone products contain only the natural testosterone molecule that is chemically produced from plant materials.
This is done as an outpatient. Since most affected individuals can not make a woman pregnant, assisted reproduction specialists are available for help IVF using sperm from the donor. Chromosomes carry our genetic information. Not all individuals with this condition have the same symptoms or to the same degree; because of this variability, cases often remain undiagnosed. They may have trouble paying attention. The vast majority of men with Klinefelter syndrome are infertile and can't father a child the usual way. Sex Chromosome Abnormalities Chromosomes are the structures that carry genes which in turn transmit hereditary characteristics from parents to offspring. There is no actual cure for this syndrome but treatments can be done to alleviate some of its symptoms, e. And many schools provide educational services or accommodations that can help your son succeed. Testosterone therapy cannot increase the size of a boy's testicles or prevent or reverse infertility, however. The Y chromosome is small, carries few genes, and has abundant repetitive sequence, while the X chromosome is more autosome-like in form and content. As they grow older, they tend to become taller than average. It also helps to improve self-esteem, mood and maintain bone health. It also prevents the testicles from producing normal amounts of sperm and the hormone testosterone. While XXY males can possibly be characterised based on physical characteristics, substantial variation in physical and developmental traits mean the only reliable method of positive or negative identification is karyotype testing. These can help improve low self-confidence, shyness, and delayed social development. In adults, possible characteristics vary widely and include little to no sign of affectedness, a lanky , youthful build and facial appearance, or a rounded body type with some degree of gynecomastia increased breast tissue. Other men may be too shy or embarrassed to approach a doctor if they are concerned about the size of their testes. If your son struggles in school or has trouble making friends, talk to your doctor, school principal, or school counselor. This disorder, also called adrenogenital syndrome AGS , results from a genetically caused deficiency of cortisol, a steroid hormone produced by the adrenal cortex. FSH levels are markedly raised as a sign of damage to the seminiferous sperm producing tubules in the testes. The issue of sexual classification, however, is complicated by factors such as chromosomal complement, external genitalia, gender identification and surgical alteration. Socially, they tend to have quiet personalities. They also can have trouble with things like learning to spell, read, and write. The frequency of males born with an additional Y chromosome is approximately 1: In 47,XXX cells, two of the X chromosomes are inactivated. Another variation is that not all cells in the affected individual have an extra X chromosome; this is known as mosaicism.
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Klinfelter, Turner, and Triple X syndrome
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